Bill & Melinda Gates Agricultural Innovations (Gates Ag One) is providing approximately 25.8 million euros (28 million US dollars) in funding for an international research project led by FAU: The non-profit organization will support the cassava source-sink (CASS) project in the next five years to improve the productivity of one of the most important food crops in sub-Saharan Africa. The project unites researchers from 11 institutions around the world to optimize cassava physiology to significantly increase the yield of high-quality cassava storage roots under low-input farming conditions in smallholder farmer fields.

Cells are the basis of life and new cells arise by dividing one cell into two cells. In animals, cell division is typically mediated by a ring-like structure consisting of long threads of actin fibers. This actin ring shrinks in size and generates the two new cells. In case actin ring constriction fails, cell division is abolished and numerous diseases can arise. The research group of Prof. Dr. Esther Zanin discovered a novel type of ring that assembles and constricts in case actin fibers are missing. The molecular composition of the novel contractile ring and how it constricts was recently published by the research group in Cell Reports

Antibodies are crucial, not only for treating tumors and infections. Sometimes, however, the immune reaction they trigger can be too strong and end up causing more damage, for example in the case of people infected with Covid-19. Problems such as these can often be avoided by finetuning antibodies, as Prof. Dr. Falk Nimmerjahn from FAU and two of his colleagues in the Netherlands and in the UK have now reported in the journal Nature Immunology.

A team of researchers at FAU and Universitätsklinikum Erlangen has gained new insights into the maturation of SARS-CoV-specific antibodies after multiple vaccinations with the mRNA vaccine Comirnaty. They have now published their work in the journal Science Immunology.

Category: Allgemein

Whether it is as a new organic fuel, innovative cancer medication or a sustainable source of food: researchers across the globe see immense potential in euglenoids. Of the 1,000 known species, only 20 have been investigated to date.

Category: Allgemein

It is essential for cells to control precisely which of the many genes of their genetic material they use. This is done in so-called transcription factories, molecular clusters in the nucleus. Researchers of Karlsruhe Institute of Technology (KIT), Friedrich-Alexander-Universität Erlangen-Nuremberg (FAU), and Max Planck Center for Physics and Medicine (MPZPM) have now found that the formation of transcription factories resembles the condensation of liquids.

Our DNA is so tightly packed that it fits into the nucleus of every cell. Our genetic library is the source of products such as RNA and proteins. The first step in the production process is called transcription. The process behind how the areas in the nucleus where transcription occurs are created was not fully understood until recently.