Research at the biochemistry division focuses on the analysis of molecular mechanisms and signal transduction pathways underlying the regulation of primary metabolism and cellular communication in plants. Applying molecular physiology and phytopathogical methods intra- as well as inter-organismic interactions are studied. Moreover, biotechnological approaches to optimize crop plants are followed.
Biotechnology (Protein structure and design, Chair)
Computational Biology (Professorship)
The Computational Biology Group focuses on the structure, dynamics, and function of biological membrane mimics, including e.g. lipid-protein interactions, membrane (nano-)domain formation, and (membrane) protein oligomerization studied both in atomistic and coarse-grained molecular dynamics simulations (Biological Membrane Biophysics).
Developmental Biology (Chair)
Our research addresses the molecular and genetic mechanisms that govern the development of embryos, tissues, and germ cells.
The developmental processes of interest include patterning of the embryonic ectoderm and mesoderm, embryonic axis formation, muscle specification and differentiation, heart development, organogenesis, germ cell and stem cell development, and tissue polarity. We are also interested in the evolutionary conservation and divergence of these processes.
Experimental Molecular Cell Dynamics (Professorship)
The aim of our research is to reveal the molecular mechanisms of cell division. In the laboratory we are using cutting-edge microscopy techniques in the model system Caenorhabditis elegans and human tissue culture cells.
The research of the division of Genetics is focused on the regulation of humoral and innate immune responses. Besides B lymphocyte development and activation, studies also focus on genetic factors which may lead to deregulated immune responses and ultimately to autoimmune diseases. Further research is directed towards the elucidation of the molecular causes of leukemia and lymphoma formation.
Mathematics in Life Sciences (Chair)
Our group is using and developing methods of statistical physics to address exciting problems in biology and medicine. We are a part of the newly established, interdisciplinary “Max-Planck-Zentrum für Physik und Medizin” in Erlangen.
Research at the Microbiology Section focuses on bacterial regulation mechanisms e.g. in Campylobacter jejuni and Helicobacter pylori. It spans from host/pathogen interactions, analyses of regulatory signaling networks and expression analyses to molecular aspects of protein/DNA, protein/protein or protein/ligand interactions.
Our research interests span different aspects of molecular microbiology including biotechnology, host-pathogen-interaction and synthetic biology. Furthermore, we are involved in teaching in a wide variety of study programs, e.g. biology, cell and molecular biology, integrated life sciences, life science engineering, molecular science etc.
Molecular Plant Physiology (Chair)
Pharmaceutical Biology (Chair)
Animal Physiology (Chair)
As neuroscientists, we are interested in questions of nervous system function with a focus on neurons and synapses and the mammalian retina as an established model system in the neurosciences.
Cell Biology (Chair)
The Cell Biology Division investigates molecular and cellular processes underlying the perception and processing of signals (e.g. light, gravity), as well as the establishment and maintenance of polarity. Experimental systems covering a wide range of the evolutionary spectrum are studied: photosynthetic protists, green algae, mosses and vascular plants.